Search results for "Older population"

showing 10 items of 24 documents

Regulatory T cells and vaccine effectiveness in older adults. Challenges and prospects

2021

Since the discovery of lymphocytes with immunosuppressive activity, increasing interest has arisen in their possible influence on the immune response induced by vaccines. Regulatory T cells (Tregs) are essential for maintaining peripheral tolerance, preventing autoimmune diseases, and limiting chronic inflammatory diseases. However, they also limit beneficial immune responses by suppressing anti-infectious and anti-tumor immunity. Mounting evidence suggests that Tregs are involved, at least in part, in the low effectiveness of immunization against various diseases where it has been difficult to obtain protective vaccines. Interestingly, increased activity of Tregs is associated with aging, …

0301 basic medicineImmunologychemical and pharmacologic phenomenaInflammationT-Lymphocytes RegulatoryAutoimmune DiseasesOlder populationImmunomodulation03 medical and health sciences0302 clinical medicineImmune systemImmunitymedicineAnimalsHumansImmunologic FactorsImmunology and AllergyAgedAged 80 and overInflammationPharmacologyVaccinesbusiness.industryVaccinationAge FactorsMembrane ProteinsPeripheral toleranceMiddle AgedVaccination030104 developmental biologyImmunization030220 oncology & carcinogenesisChronic DiseaseImmunologymedicine.symptomOlder peoplebusinessImmunosuppressive AgentsInternational Immunopharmacology
researchProduct

Mean temperature and humidity variations, along with patient age, predict the number of visits for renal colic in a large urban Emergency Department:…

2012

Background: A marked geographic variability has been reported in stone disease, partially attributed to the Mean Annual Temperature (MAT), as well as to the seasonal fluctuations of climatic conditions. Accordingly, peaks in Emergency Department (ED) visits for renal colic are commonplace during the summer. Materials and methods: The aim of this study was to assess the influence of day-by-day climate changes on the number of visits as a result of renal colic in the ED (City of Parma, northern Italy, temperate continental climate). A total of 10,802 colic episodes were retrieved from the database during a period of 3286 days (January 2002 to December 2010). Results: The analysis of the data …

AdultMalePediatricsmedicine.medical_specialtyDatabases FactualEpidemiologyClimateRisk AssessmentSeverity of Illness IndexArticleOlder populationCohort StudiesYoung AdultAgeHospitals UrbanPatient agePredictive Value of TestsEpidemiologymedicineHumansRenal colicMean radiant temperatureRenal ColicStone diseaseAgedRetrospective StudiesAged 80 and overAnalysis of Variancebusiness.industrylcsh:Public aspects of medicineIncidenceTemperatureAge Factorslcsh:RA1-1270HumidityEmergency departmentMiddle AgedNorthern italyItalyLinear ModelsFemaleSeasonsmedicine.symptombusinessEmergency Service HospitalJournal of Epidemiology and Global Health
researchProduct

Challenges in the pharmacological treatment of geriatric asthma

2016

ABSTRACTAsthma in older populations is characterized by frequent comorbid conditions, which increase the risk of side effects and of detrimental interactions between respiratory and non-respiratory drugs. These observations lead to the need to manage asthma in older populations by applying a multidimensional assessment and a multidisciplinary treatment; therefore, we favor the use of the ‘geriatric’ term to define asthma in the elderly. Geriatric asthma is a complex disease, which may not necessarily imply that it is also complicated, although the two conditions may often coexist. On this basis, the switch from an organ-driven management to the holistic approach may be the key factor to att…

Agingmedicine.medical_specialtyComplex diseaseComorbidityDiseaseSettore MED/10 - Malattie Dell'Apparato RespiratorioAnti-asthmatic AgentPharmacological treatmentOlder population03 medical and health sciences0302 clinical medicineMultidisciplinary approachAnimalsHumansMedicinePharmacology (medical)Anti-Asthmatic Agents030212 general & internal medicineGeneral Pharmacology Toxicology and PharmaceuticsIntensive care medicinePsychiatryAgedAsthmabusiness.industryAge FactorsGeneral Medicinemedicine.diseaseComorbidityAsthmaInhaled treatment030228 respiratory systemAdherencePharmacology Toxicology and Pharmaceutics (all)businessExpert Review of Clinical Pharmacology
researchProduct

Intergenerational Caregiving. Young Auxiliary Caregivers

2010

In 2009, an estimated 737 million persons of the world population were older than 60. More than half of this older population, 54%, live in Asia, and one fifth, 21%, live in Europe. This number wil...

ArcheologyGeographySociology and Political ScienceSocial PsychologyWorld populationGeriatrics and GerontologyLife-span and Life-course StudiesSocial Sciences (miscellaneous)DemographyOlder populationJournal of Intergenerational Relationships
researchProduct

Why People Born During World War II are Healthier

2017

War leads civilians to suffer. This can take extreme forms, such as during periods of intense violence or famines. But also outside of such episodes, civilians’ lives during wars can be harsh, as they suffer from poorer nutritional situations, stress, recessions, and sub optimally functioning health care systems. The more extreme types of suffering are proven to lead to a worse health among those prenatally exposed to them. But long-run effects of prenatal exposure to the latter circumstances have thus far largely been unexplored, even though in many wars more pregnant women are exposed to these “everyday” circumstances than to the extreme circumstances. We study the general, population-wid…

Economic growthHistorybusiness.industrymedia_common.quotation_subjectWorld War IIFertilityRecessionOlder populationSpanish Civil WarHealth careFaminebusinessPrenatal exposureDemographymedia_commonSSRN Electronic Journal
researchProduct

Validation of the University of California, Los Angeles Loneliness Scale (version 3) in Spanish older population: An application of exploratory struc…

2020

Loneliness is a subjective and unpleasant experience associated to a variety of physical and mental health problems. Older people face an elevated risk of loneliness. It is measured through self‐re...

Gerontology050103 clinical psychology05 social sciencesLonelinessMental healthConfirmatory factor analysisStructural equation modeling030227 psychiatryOlder population03 medical and health sciences0302 clinical medicineArts and Humanities (miscellaneous)Quality of lifeScale (social sciences)medicine0501 psychology and cognitive sciencesmedicine.symptomOlder peoplePsychologyGeneral PsychologyAustralian Psychologist
researchProduct

The current state and developments in higher education in gerontology in the Nordic countries

2012

The growing size of the older population challenges not only researchers but also higher education in gerontology. On the basis of an online survey the authors describe the situation of Nordic higher education in gerontology in 2008 and 2009 and also give some good examples of Nordic- and European-level collaboration. The survey results showed that gerontological education was given in every Nordic country, in 31 universities and 60 other higher education institutions. Although separate aging-related courses and modules were relatively numerous, programs for majors were relatively few. Networking in the Nordic region offers a good example on how to further develop higher education in geront…

GerontologyEconomic growthInternationalityHigher educationmedia_common.quotation_subjectPopulation DynamicsSurvey resultEducationOlder populationState (polity)Surveys and QuestionnairesHumansMedicineCooperative BehaviorFinlandmedia_commonbusiness.industryta3141ta3142Quality ImprovementTrend analysisEducation Medical GraduateGeriatricsCurriculumEducational MeasurementGeriatrics and GerontologybusinessNeeds AssessmentGerontology & Geriatrics Education
researchProduct

Prevalence of root caries among elders living in residential homes of Bengaluru city, India

2015

Background: Among the various oral ailments which have been observed in elderly, root caries is a significant one. Tooth loss is chief oral health-related negative variable to the quality of life in elderly and root caries is the major cause of tooth loss in them. It has been reported about a third of older population bears most of the root caries burden, so the present study aimed to assess the prevalence of root caries among older individuals residing in residential homes of Bengaluru city India. Material and Methods: Elderly individuals aged 60 and above, residing in residential homes of Bangalore city, were included in the study. The study participants filled a questionnaire regarding t…

GerontologyPopulationOdontologíaOral healthOlder population03 medical and health sciences0302 clinical medicineQuality of life030502 gerontologyEnvironmental healthTooth lossMedicineeducationGeneral DentistryRoot carieseducation.field_of_studyDescriptive statisticsbusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludCommunity and Preventive DentistryUNESCO::CIENCIAS MÉDICASMarital statusmedicine.symptom0305 other medical sciencebusiness
researchProduct

Equality according to whom? Debating an age-related restriction in the upcoming disability legislation reform in Finland

2020

Within many countries, the policies of disability and old age have been developing on distinct paths. Even though the prevalence of disability is higher in older populations, older persons tend to be excluded from disability discourses. Taking Finland's disability service legislation reform as an example, this article elaborates on the justifications for excluding or including older persons from disability policies. The paper analyses the public statements given in 2017 to a proposal that introduced an age-related restriction to disability services in order to understand how the restriction is argued for and against, and what kind of conceptualisations of old age and disability the statemen…

Health (social science)media_common.quotation_subjectvammaisetPublic policyPublic PolicyLegislationOlder populationOrder (exchange)Age relatedHumansDisabled PersonsSociologyLife-span and Life-course StudiesFinlandAgedmedia_commonAged 80 and overvammaispolitiikkaGeneral Arts and HumanitiesGeneral Social SciencesGender studiesGeneral Medicinevammaispalveluttasa-arvoService (economics)ikääntyneet
researchProduct

Mediterranean Diet Maintained Platelet Count within a Healthy Range and Decreased Thrombocytopenia-Related Mortality Risk: A Randomized Controlled Tr…

2021

There is little information on the dietary modulation of thrombosis-related risk factors such as platelet count. We aimed to assess the effects of Mediterranean diet (MedDiet) on platelet count and related outcomes in an older population at high cardiovascular risk. In participants of the PREDIMED (PREvención con DIeta MEDiterránea) study, we assessed whether an intervention with a MedDiet enriched with extra-virgin olive oil or nuts, relative to a low-fat control diet, modulated platelet count (n = 4189), the risk of developing thrombocytosis and thrombocytopenia (n = 3086), and the association between these alterations and all-cause mortality (median follow-up time: 3.0 years). Although p…

Male0301 basic medicineMediterranean dietthrombocytopenia030204 cardiovascular system & hematologyDiet Mediterraneanlaw.inventionClinical trials0302 clinical medicinepreventionRandomized controlled triallawPlateletThrombocytosisNutrition and DieteticsFactors de risc en les malaltiesIncidenceIncidence (epidemiology)Hazard ratioFemaleDietalcsh:Nutrition. Foods and food supplymedicine.medical_specialtyRisk factors in diseaseslcsh:TX341-641ArticleOlder population03 medical and health sciencesMediterranean cookingMediterranean dietInternal medicineCuina mediterràniamedicineHumansAgedProportional Hazards ModelsThrombocytosisPlatelet Countbusiness.industryplatelet countmedicine.diseaseConfidence intervalDiet030104 developmental biologyHeart Disease Risk Factorsrandomized controlled trialbusinessAssaigs clínicsFood ScienceNutrients
researchProduct